Ram Gopal College of Pharmacy

Approved by- AICTE, PCI, MHRD, Govt of India,
Affiliation from Pt. B.D. Sharma University of Health Science, Rohtak, Haryana
State Government University

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  • Notification

  • Admission Open 2020-21
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  • Last date of Submission of Form
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  • Facilities at RGCP
    RGCP Pharmacy College in Delhi NCR

    The institute provides with transport facility from all parts of delhi and Gurgaon.


    Admission open for 2020-21 M.Pharmacy (Pharmaceutics), B.Pharmacy - LEET Limited Seats Available

    PHYTOPHARMACOLOGY OF TURMERIC

    Abstract

    Turmeric is an herbaceous evergreen plant in the Zingiberaceae (ginger) family. Turmeric ( Curcumalonga) is extensively used as a spice, food preservative and colouring material in India, China and South East Asia. Turmeric powder is best known as one of the main ingredients used to make the curry spice; it also gives ballpark mustard its bright yellow colour. Apart from its culinary uses, turmeric has been used widely in the traditional medicine all over the world. Curcumin (diferuloylmethane), the main yellow bioactive component of turmeric has been shown to have a wide spectrum of biological actions. These include its antiinflammatory, antioxidant, anticarcinogenic, antimutagenic, anticoagulant, antifertility, antidiabetic, antibacterial, antifungal, antiprotozoal, antiviral, antifibrotic, antivenom, antiulcer, hypotensive and hypocholesteremic activities.

     

    Introduction

    Turmeric is an herbaceous evergreen plant in the Zingiberaceae (ginger) family. It is cultivated

    extensively in Asia mostly in India and China. Probably originated from India, turmeric has

    been used in India for at least 2500 years. Turmeric plant is distributed throughout tropic and

    subtropical region of the world.

       Turmeric is a sterile plant and does not produce any seeds. The plant grows up to 3-5 ft tall

    and dull yellow flowers. The rhizome is an underground stem that is thick and fleshy ringed

    with the bases of old leaves is part of turmeric which posses a potential medicinal property.

    Rhizomes are boiled and then dried and ground to make the distinctive bright yellow spice. Turmeric powder has a peppery bitter flavour and a mild fragrance slightly reminiscent of

    orange and ginger.

     

    Phytoconstituents of turmeric

    Turmeric contains 69.4% carbohydrates, 6.3% protein, 5.1% fat, 3.5% minerals, and 13.1%. moisture. The essential oil (5.8%) obtained by steam distillation possesses Sesquiterpenes (53%), zingiberene (25%), a-phellandrene (1%), sabinene (0.6%), cineol (1%), and borneol (0.5%). Curcumin (3–4%) is responsible for the yellow colour, and comprises curcumin I (94%), curcumin II (6%) and curcumin III (0.3%). Presence of tumerone a, tumerone b, curzerenone, curdione, mono- and di-demethoxycurcumin have been reported in the rhizomes

     

    Phytopharmacology of turmeric

    Turmeric has several therapeutic and pharmacologic activities. The following is the most important phytopharmacology and therapeutic properties of turmeric.

     

    1.       Antioxidant activity

    Curcumin has been shown be a powerful scavenger of oxygen free radicals. Its antioxidant activity is comparable to vitamins C and E (4). It can protect lipids or hemoglobin from oxidation. It can significantly inhibit the generation of reactive oxygen species (ROS) such as H2O2, superoxide anions and nitrite radical generation by activated macrophages.

     

    2.       Cardiovascular and anti-diabetic effects

    Turmeric exerts cardio-protective effects mainly by antioxidant activity, lowering lipid peroxidation, anti-diabetic activity and inhibiting platelet aggregation. Both turmeric decreases blood glucose level in diabetic rats. Turmeric also decreases complications in diabetes mellitus.

     

    3.       Inflammatory and edematic disorders

    Curcumin is a potent anti-inflammatory with specific lipoxygenase- and COX-2- inhibiting properties. In vitro, and in vivo studies have demonstrated its effects at decreasing both acute and chronic inflammation.

     

      Conclusion

    Turmeric is the unique source of various types of chemical compounds, which are responsible for a variety of activities.

     

    Ketki Shori

    Assistant Professor

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    College At:- Near Sultanpur Bird Sanctuary,
    Farrukhnagar, Distt.- Gurgaon, Haryana
    Phone:- 09310480029

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    A1/11, Prashant Vihar Rohini,
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